GIUSEPPE ALVARO,SANDRO BELVEDERE,ROMANO DI FABIO,ALESSANDRO FALCHI,RICCARDO GIOVANNINI,DANIELE ANDREOTTI
申请号：
MYPI 20064110
公开号：
MY145713A
申请日:
2006.09.07
申请国别(地区):
MY
年份:
2012
代理人:
摘要：
THERE ARE PROVIDED ACCORDING TO THE INVENTION NOVEL COMPOUNDS OF FORMULA (L) OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF: WHEREIN: X REPRESENTS A NITROGEN ATOM； Y REPRESENTS -C(H2)-, (-C(H2)-)2, -S(02)-OR -C(=O)-； Z REPRESENTS -C(H2)-, -S(02)-, -N(RZ)-, OR AN OXYGEN OR SULPHUR ATOM； A REPRESENTS HYDROGEN OR -CH2OH； RZ REPRESENTS HYDROGEN, C1-6 ALKYL, CL-6 ALKOXY, -COR7 OR -SO2R 7； R1 REPRESENTS HALOGEN, CL-6 ALKYL, C1-6 ALKOXY, =O, HALOC1-6 ALKYL, HALOC1-6 ALKOXY, HYDROXYL OR -CH2OH； M REPRESENTS AN INTEGER FROM 0 TO 3； R2REPRESENTS HALOGEN, =O1, C1-6 ALKYL (OPTIONALLY SUBSTITUTED BY ONE OR MORE HYDROXYL GROUPS), -COOR 7, -CONR7R8, C1-6 ALKOXY, HALOC1-6 ALKYL, HALOC1-6ALKOXY OR C1-6ALKYLOC1- 6ALKYL； N REPRESENTS AN INTEGER FROM 0 TO 3； P AND Q INDEPENDENTLY REPRESENT AN INTEGER FROM 0 TO 2； R3 REPRESENTS AN-ARYL, -HETEROARYL, -HETEROCYCLYL, -ARYL-ARYL, -ARYL-HETEROARYL, -ARYL-HETEROCYCLYL, -HETEROARYL-ARYL, -HETEROARYL-HETEROARYL, -HETEROARYL-HETEROCYCLYL, -HETEROCYCLYL- ARYL, -HETEROCYCLYL-HETEROARYL OR -HETEROCYCLYL-HETEROCYCLYL GROUP, ALL OF WHICH MAY BE OPTIONALLY SUBSTITUTED BY ONE OR MORE (E.G. 1, 2 OR 3) HALOGEN, C1-6 ALKYL (OPTIONALLY SUBSTITUTED BY ONE OR MORE HYDROXYL GROUPS), C3-8 CYCLOALKYL, C1-6 ALKOXY, HYDROXYL, HALOC1-6 ALKYL, HALOC1-6 ALKOXY, CYANO, -S-CI-6 ALKYL, -SO-C1-6 ALKYL, -SO2-C1-6 ALKYL, -COR7, -CONR7R8. –NR7R8, -NR7COC1-6 ALKYL, -NR7 SO2-C1-6 ALKYL, C1-6 ALKYL-NR7R8, -OCONR7R8, - NR7CO2R8 OR -SO2NR7R8 GROUPS； R4 AND R5 INDEPENDENTLY REPRESENT C1-6 ALKYL, OR R4 AND R5 TOGETHER WITH THE CARBON ATOM TO WHICH THEY ARE ATTACHED MAY TOGETHER FORM A C3-8 CYCLOALKYL GROUP； R6 REPRESENTS HALOGEN, C1-6 ALKYL, C3-8 CYCLOALKYL, CL-6 ALKOXY, HALOC1-6 ALKYL OR HALOC1-6 ALKOXY； S REPRESENTS AN INTEGER FROM 0 TO 4； R7 AND R8 INDEPENDENTLY REPRESENT HYDROGEN, C1-6 SLKYL OR C3-8 CYCLOALKYL； OR SOLVATES THEREOF
