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Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
专利权人:
Corcept Therapeutics Inc.
发明人:
Johnson Tony,Ray Nicholas,Hunt Hazel,Walters Iain
申请号:
NZ70146913
公开号:
NZ701469A
申请日:
2013.05.24
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
The present Invention provides heteroaryl ketone fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators. In some embodiments, the present invention provides a pharmaceutical cmnposition including a pharmaceutically acceptable excipient and the compound of formula I. In some embodiments, the present invention provides a method of modulating a glucocorticoid receptor, the method including contacting a glucocorticoid receptor with a compound of formula I, thereby modulating the glucocorticoid receptor, as well as a method of treating a disorder through modulating a glucocorticoid receptor, the method including administering to a subject in need of such treatment, a therapeutically eftective amount of a compound of formula (I), thereby treating the disorder.
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