PROBLEM TO BE SOLVED: To provide an anti-tumor agent obtained by improving the solubility to water of a platinum-based anti-tumor agent, increasing the anti-tumor effect by selectively accumulating/staying the agent at the tumor part and decreasing adverse effects to normal organ tissues.SOLUTION: A polymer type anti-tumor agent is provided by containing an ionically bonded material expressed by formula [I] [wherein, (m) is an integer to make 60 to 160 nm fluid dynamics diameter of the high polymer type anti-tumor agent R1, R2 are each NH3, an amine or the like (n) is an integer of 0 to 5 and R3 is one selected from the group consisting of alkyl, alkoxy, carboxy, methanesulfonyloxy, trifluoromethanesulfonyloxy, nitro, nitrile and sugar or oligosaccharide, or substituted or non-substituted methylene dioxy constituted by R3 bonding with two carbon atoms adjacent with each other] as an active ingredient.COPYRIGHT: (C)2013,JPO&INPIT【課題】白金系抗腫瘍剤の水溶性を改善し、腫瘍部に選択的に集積・滞留させて抗腫瘍効果を増大させ、正常器官組織への副作用を軽減した抗腫瘍剤の提供。【解決手段】式[I]で表されるイオン結合体を有効成分として含む高分子型抗腫瘍剤。式中、mは高分子型抗腫瘍剤の流体力学直径が60nm~160nmとなる整数であり、R1とR2は、NH3、アミン等であり、nは0~5の整数であり、R3はアルキル、アルコキシ、カルボキシル、メタンスルホニルオキシ、トリフルオロメタンスルホニルオキシ、ニトロ、ニトリル、及び糖若しくはオリゴ糖からなる群から選ばれる一種、若しくは隣り合った二つの炭素に結合するR3が構成する置換若しくは非置換のメチレンジオキシ基である。【選択図】なし
