XIAO, SHOUHUA,PAN, ZHENG,WICKRAMASINGHE, DINELI,JEFFRIES, M., SHAWN,KING, CHADWICK TERENCE,CHAN, BRIAN MINGTUNG,KUFER, PETER,LUTTERBUESE, RALF,RAUM, TOBIAS,HOFFMANN, PATRICK,RAU, DORIS,KISCHEL, ROMAN
申请号：
HK15112611.7
公开号：
HK1211946A
申请日:
2015.12.23
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present invention provides to a antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target cell and a second domain capable of binding to human CD3 on the surface of a T cell. Moreover, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention relates a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
