Jason Shaoyun XIANG,Shifeng LIU,Hongyu YANG,Xingquan MA
申请号:
US15580895
公开号:
US20180161446A1
申请日:
2016.06.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are an antibody drug conjugate IB, which uses ether linkages for connection, and improves the water solubility, stability and cytotoxicity in vivo and in intro, and an intermediate, a pharmaceutical composition, and uses of the antibody drug conjugate. The antibody drug conjugate has simple synthetic steps and a high yield.