EVALUATION METHOD AND SCREENING METHOD FOR S1P1 RECEPTOR AGONIST

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专利权人:

MEIJI SEIKA PHARMA CO.; LTD.

发明人:

NINOMIYA, TOMOHISA,YOSHIDA, SATOSHI

申请号：

CA2919980

公开号：

CA2919980A1

申请日:

2014.08.20

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

It was discovered that the main effect (immunosuppressive activity) of S1P1 receptor agonists correlates with the selectivity for cells expressing a combination of S1P1 receptors and Gai2 or Gai3, and that the side effect (cardiotoxicity) of S1P1 receptor agonists correlates with the selectivity for cells expressing a combination of S1P1 receptors and Gai1.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/