A physiological monitoring system includes an electrocardiogram (ECG) module and a main module connected by a first communication connection that is wireless. The main module receives the first physiological data from the ECG module using the first communication connection. The main module stores the physiological data and transmits alerts using both wireless or wired communication connections. The ECG module can identify one or more abnormal conditions of the patient, and transmit in real-time results of the analysis to the main module using the first communication connection and/or transmit alerts or alarms directly to the patient's skin. Additionally, a detachable pre-cordial electrode array can be added that includes a second plurality of electrodes worn in a precordial location of the patient to gather second physiological data and transmits the second physiological data to the ECG module or the main module.