AYESA, SUSANA,GRABOWSKA,URSZULA,HEWITT, ELLEN,JOENSSON, DANIEL,KLASSON, BJOERN,KAHNBERG, PIA,LUNDGREN, STINA,TEJBRANT, JAN,WIKTELIUS, DANIEL
申请号：
EP11795278
公开号：
EP2582660A4
申请日:
2011.06.16
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
There is provided a process for the preparation of a compound of formula III, comprising the step of oxidising the compound of formula 2b wherein n is 2； R 2a and R 2b are independently H or F； R 3 is 1-methylcyclopentylmethyl or 1-fluorocyclopentylmethyl； R 3' is CH 3 or F； R 4 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl or C 3 -C 6 cycloalkyl, wherein C 3 -C 6 cycloalkyl is optionally substituted with methyl, CF 3 or one or two fluoro. Compounds and processes used in the preparation of a compound of formula III are also provided.
