Inhibitors of the kinase activity, particularly the activity of PL3 Kinases.Claim 1: a compound of formula (1),In the r\u00b9 is N (c\u2081\u208b\u2086 alkoxy or alkyl c\u2081\u208b\u2086) \u2082 R\u00b2 is Hydrogen or optionally substituted alkyl c\u2081\u208b\u2086 - C (o) - alkyl or alkyl - or c\u2081\u208b\u2086 oC (OR) alkyl c\u2081\u208b\u2086 r\u00b3, r\u2074,R\u2075 r\u2076 are selected and each independently Hydrogen and Halogen and r\u2077 r\u2078 are each independently c\u2081\u208b\u2086 alkyl, or r\u2077 and r\u2078, along with the nitrogen Atom to which they are UnitedThey Unite to form a heterociclilo 5 or 6 members where the heterociclilo 5 or 6 members optionally contains an additional nitrogen Atom and is optionally substituted with cicloalquILO c\u2083\u208b\u2086, a heterociclilo 4 to 6 members that contains one or two heteroatoms selected irrespective of oxygen and NitrogenWhere the alkyl or alkyl c\u2081\u208b\u2086 c\u2081\u208b\u2086 is optionally substituted with Hydroxy or alkoxy c\u2081\u208b\u2086, or r\u2077 and r\u2078, along with the nitrogen Atom to which they are UnitedThey Unite to form a heterociclilo 5 or 6 members where the heterociclilo 5 or 6 members contains an oxygen Atom and is optionally substituted with one or two independent substituentsDently selected from alkyl c\u2081\u208b\u2086 or a Salt thereof.