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INHIBITEURS DE PROTEASOME ET METHODES LES UTILISANT
专利权人:
CEPHALON; INC.
发明人:
CHATTERJEE, SANKAR,IQBAL, MOHAMED,MENTA, ERNESTO,OLIVA, AMBROGIO
申请号:
CA2536518
公开号:
CA2536518C
申请日:
2004.08.13
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention provides for boronic acid compounds, boronic esters, andcompositions thereof that can modulate apoptosis such as by inhibition ofproteasomeactivity. The compounds and compositions can be used in methods in inducingapoptosis and treating diseases such as cancer and other disorders associateddirectlyor indirectly with proteasome activity. The compounds of the invention arerepresented by general formula [I] below.(see formula I)
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