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PHARMACOLOGICAL PROPHYLACTICS AGAINST STRESS-INDUCED AFFECTIVE DISORDERS AND THEIR ASSOCIATED SYMPTOMS
专利权人:
The Trusttees of Columbia University in the City of New York
发明人:
Rebecca Anne BRACHMAN,Christine Ann DENNY,René HEN
申请号:
US15776880
公开号:
US20180325844A1
申请日:
2016.11.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods for prophylactically treating a stress-induced affective disorder or stress-induced psychopathology in a subject are provided. Also provided are methods for inducing and/or enhancing stress resilience in a subject. In certain embodiments, an effective amount, of an antagonist of the glutamate N-methyl-D-aspartate (NMDA) receptor, such as ketamine, or a pharmaceutically acceptable salt or derivative thereof, is administered to a subject prior to a stressor.
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