Troy E. Messick,Garry R. Smith,Allen B. Reitz,Paul M. Lieberman,Mark E. McDonnell,Yan Zhang,Venkata Velvadapu
申请号：
US15036211
公开号：
US09856214B2
申请日:
2014.11.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides EBNA1 inhibitors, and pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The compounds and compositions of the invention are further useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. The compounds and compositions of the invention are further useful for the treatment of diseases caused by lytic EBV infection.
