The sanitizer door knob system has a door knob assembly that emits sanitizing liquid when turned in either direction. In a set, only one knob will emit the sanitizer fluid. The inside of the knob that does emit the liquid has a pull rod that pulls an internal pump upon the turning of the knob and cause the sanitizing liquid to be projected from its reservoir tube. A slider cap on the exterior of the knob opens to allow the sanitizer to be emitted. Door knob assembly may comprise a recoil spring on both the first and second door knob.