A biopsy device comprises a body, a needle, and a needle firing assembly. The needle comprises a sharp tip and a hub. The hub comprises a distal flange and a proximal flange. The needle firing assembly is operable to drive the needle longitudinally relative to the body. The needle firing assembly comprises a fork member coupled with the hub of the needle. The fork member comprises a pair of distal ramped surfaces converging at a distal edge configured to engage the distal flange. The fork member further comprises a pair of proximal ramped surfaces converging at a proximal edge configured to engage the proximal flange.