Seattle Children's Hospital (dba Seattle Children's Research Institute)
发明人:
Jensen, Michael C.,Matthaei, James
申请号:
AU2018219226
公开号:
AU2018219226A1
申请日:
2018.02.06
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Aspects of the invention described herein relate to synthetic compounds that are useful for targeting and labeling tumor cells so as to facilitate recognition by binding agents including Chimeric Antigen Receptor T cells (CAR T cells), which are administered to a subject by intravenous or locoregional administration. Several compositions and methods of making and using these compositions to treat or inhibit a disease in a subject are contemplated.