Ectodomains of influenza Matrix 2 protein, expression system, and uses thereof

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专利权人:

Emergent Product Development Gaithersburg Inc.

发明人:

Guina, Tina,Lacy, Michael,Skiadopoulos, Mario,Mytle, Nutan

申请号：

AU2011230491

公开号：

AU2011230491A1

申请日:

2011.03.28

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention provides a polynucleotide, polypeptide, recombinant modified vaccinia virus Ankara (rMVA) and related vaccine compositions and methods useful in the prevention and treatment of an influenza viral infection. Provided is an isolated polynucleotide encoding multiple copies of M2 infuenza ectodomain peptides or rMVA comprising the polynucleotide. Also provided are methods for inducing an immune response to a subject against an influenza virus or for treating a disease or symptom caused by or resulting from infection with an influenza virus.

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