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Pyridonaphthyridine-type PI3K and mTOR dual inhibitors and their preparation and use
专利权人:
シュアンジュ・ファーマ・カンパニー・リミテッド
发明人:
▲呉▼ 永▲謙▼,▲張▼ ▲艷▼
申请号:
JP2014513033
公开号:
JP5878628B2
申请日:
2012.06.04
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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