In a cytotoxic compound of the general formula (I) R is H or methyl or methylene substituted by C1-C4 straight or branched alkyl, R1 is selected from the group consisting of H, C1-C4 straight or branched alkyl, methoxy, methoxy substituted by from one to three fluorine, halogen R2 is H or C1-C4 straight or branched alkyl X is CH or N Y is CH or N.En un compuesto citotóxico de la Fórmula General (I), R es H o metilo o metileno sustituido por alquilo C1-C4 lineal o ramificado, R1 es seleccionado del grupo que consiste de H, alquilo C1-C4 lineal o ramificado, metoxi, metoxi sustituido por de uno a tres flúor, halógeno R2 es H o alquilo C1-C4 lineal o ramificado X es CH o N Y es CH o N.