Van Der Graaf, Adrianus Cornelis,Schmidt, Martina,Euverink, Gerrit Jan Willem,Meurs, Hermanus,Henning, Robert Henk
申请号:
AU2015276186
公开号:
AU2015276186A1
申请日:
2015.06.17
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to compounds for the treatment of chronic obstructive airway diseases such as chronic obstructive pulmonary disease (COPD) or asthma or bronchiectasis. The present invention further relates to drug delivery devices suitable to be used in the treatment of chronic obstructive airway diseases such as a nebulizer comprising the present compounds. Specifically, the present invention relates to (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(piperazin-1-yl)methanone or N,6-dihydroxy-2,5,7,8-tetramethylchroman-2-carboxamide or a pharmaceutically acceptable salt or base thereof for use in the treatment of chronic obstructive airway diseases, preferably chronic obstructive pulmonary disease (COPD) or asthma or bronchiectasis, more preferably chronic obstructive pulmonary disease (COPD).