Compounds having unique antiviral properties found in mushroom mycelium and their analogs are extracted, concentrated, isolated, synthesized or manufactured to create compositions useful in preventing the spread and proliferation of various viruses afflicting animals, particularly viruses harming humans, pigs, birds, bats, or bees. Such compounds and compositions can be used individually or in combination with known medicines or natural products such as mushroom mycelium and extracts of mushroom mycelium to improve health.