LACORTE, Andrea,TARANTINO, Germano,BONDIOLI, Paolo
申请号:
IBIB2016/054788
公开号:
WO2017/029580A1
申请日:
2016.08.09
申请国别(地区):
IB
年份:
2017
代理人:
摘要:
The present invention relates to a process for preparing a mixture of cetylated fatty acids and a system for carrying out said process. Furthermore, the present invention relates to a composition comprising, or alternatively, consisting of said mixture of cetylated fatty acids. Finally, the present invention relates to said composition for use in the treatment and/or prevention of: (i) rheumatoid arthritis of inflammatory and non-inflammatory origin, in particular osteoarthritis; (ii) other inflammatory joint conditions; (iii) psoriasis, lupus, periodontal diseases or cardiovascular or heart diseases; (iv) all post-traumatic osteoarticular pathologies including sports injuries; (v) all degenerative joint pathologies (arthrosis, gonarthrosis, coxarthrosis, etc.), and (vi) inflammatory-traumatic tendon and muscular conditions. Furthermore, it is envisaged that the composition of the present invention be used in the treatment and/or prevention of the above-mentioned pathologies and disorders (i)-(vi) in association with a rehabilitative therapy. The composition comprising said mixture is formulated in a pharmaceutical form for oral use (novel food, supplement or medical device), i.e. in the form of a pill, pastille, capsule, tablet, granules, dispersible powder, syrup, solution or sprayable solution; for topical use, i.e. in the form of a cream, unguent, ointment, gel or spray to be used as such for application on the skin, or else for transdermal use in the form of a patch.La présente invention concerne un procédé de préparation d'un mélange d'acides gras cétylés et un système pour la mise en œuvre dudit procédé. Une composition comprenant, ou en variante, constituée dudit mélange d'acides gras cétylés est en outre décrite. Pour finir, la présente invention concerne ladite composition pour son utilisation dans le traitement et/ou la prévention de (i) la polyarthrite rhumatoïde d'origine inflammatoire et non inflammatoire, en particulier l'arthrose; (ii) d'autres affec