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COLLAGEN COATED ARTICLE
专利权人:
Christina Gretzer;Matthias Mörgelin
发明人:
Christina Gretzer,Matthias Mörgelin
申请号:
US13493191
公开号:
US20120316646A1
申请日:
2012.06.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides a biocompatible article having a surface comprising collagen fibrils attached to said surface via one or more linker molecules, wherein each of said collagen fibrils is attached to at least one of said one or more linker molecules at a proximal end of the fibril, and wherein each of said collagen fibril has a proximal portion extending from said proximal end to a point P along said fibril, wherein, for a majority of said fibrils, each fibril at said point P is oriented so as to form an angle αP in the range of 0° to 45° to the surface normal N at the point of attachment of said fibril to said surface. The collagen fibril-coated surface has improved biocompatibility and is useful in a medical implant intended for implantation into soft tissue or bone tissue.
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中国工程科技知识中心
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