Emmie DE WIT,Monique I.J. Spronken,Ron A.M. Fouchier,Albert D.M.E. Osterhaus
申请号：
US13088120
公开号：
US20120156241A1
申请日:
2011.04.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to the field of influenza vaccine production. Influenza vaccines have been produced in embryonated hens eggs for over 50 years, but recently there have been considerable efforts to develop cell culture systems for vaccine production. In one embodiment, the invention provides a nucleic acid comprising an influenza gene segment and a bacteriophage polymerase promoter or a complementary strand of said nucleic acid, and a cell comprising such a nucleic acid capable of producing desired influenza virus. In another embodiment, the invention provides a composition comprising a cell or material derived from a cell according to the invention and a virus or material derived from a viral particle according to the invention.
