The present specification discloses compositions comprising one or more silicon dioxide-based particles comprising, consisting essentially of or consisting of one or more active agents and methods and uses for the disclosed compositions. A composition disclosed herein can be incorporated into a body wash, an after-shower body lotion, a shampoo, a conditioner, a soap, a gel, a hand sanitizer, a cream, a spray, a mousse, a lotion, an ointment, a powder, a stick, an injectable, an ingestable, a make-up product, a lip balm, a hair spray product, an arachnid/insect repellent, a cosmetic product, or a medicinal product.