METHODES ET COMPOSITIONS UTILISANT DES INHIBITEURS DE LA PHOSPHODIESTERASE 4 (PDE4) POUR LE TRAITEMENT ET LA PRISE EN CHARGE DE MALADIES AUTO-IMMUNES ET INFLAMMATOIRES
Methods of treating, preventing, or managing autoimmune inflammatory diseases and disorders including but not limited to spondylitis, juvenile rheumatoid arthritis, psoriasis, psoriatic arthritis, osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis by the administration of phosphodiesterase 4 (PDE4) inhibitors in combination with other therapeutics are disclosed. Pharmaceutical compositions, dosage forms, and kits suitable for use in methods of the invention are also disclosed.