PHARMACEUTICAL COMPOSITION OF [ (3-HYDROXY-4 -PYRON-2-YL) METHYL] -AMINE DERIVATIVES AND DNA DEMETHYLATING AGENTS AND THEIR USE AS ANTI-NEOPLASTIC DRUGS

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专利权人:

UNIVERSITA' DEGLI STUDI DI URBINO "CARLO BO"

发明人:

Micro Fanelli,Vieri Fusi

申请号：

US16312560

公开号：

US20190209552A1

申请日:

2017.06.30

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The present invention concerns pharmaceutical compositions comprising compounds with general formula I or poly-alkyl-bis-maltolic molecules and in particular derivatives of [(3-hydroxy-4-pyron-2-yl)methyl]-amine in combination with DNA demethylating agents as anti-neoplastic drugs. In particular, for the preparation of a medicament for the treatment of neoplastic pathologies.

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