VRAJESH PANDYA,HARIKISHOR PINGALI,PANKAJ MAKADIA,SAIRAM V. V. M. KALAPATAPU
申请号：
ARP120102309
公开号：
AR086776A1
申请日:
2012.06.27
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
Pharmaceutical ingredients containing these substances and their use in medicine These compounds are suitable for the treatment of diseases such as hyperlipidemia. Characteristic 1: formula compound (1) with ceramic form, stereoisomer, pharmaceutically acceptable salts and pharmaceutical components containing such compound, and its characteristic is: Za represents a simple alternative group or a combination group selected from arilo, isomerization or cyclopentyl subgroup； each An X and Z independently represent a combined or simple alternative group selected from the arilo, isopropene or cyclopropene groups；Alternatively, z-x-za can be combined to form a fusion ring system composed of 8-15 three cycle members, including 1-4 heteroatoms selected from n or s； R1,R² and R³ independently at each occurrence represent H, C₁₋₆ linear or branched alkyl, C₁₋₆ linear or branched alkenyl, C₁₋₆ linear or branched alkynyl, alkynyl, hydroxy, C₁₋₆ alkoxy,Cque alkenoxy,alquil C hidroxi alcoxialquilo haloalquilo cicloalquilo CC₁₋₆ thioalkyl,1. C8332121 asphalt；halo oxo imino nitro arilo heterociclilo amino opcionalmente sustituido amino alquilo Calkylamino, cyano, formyl, haloalkoxy, aryl, aryloxy, aralkyl, aralkoxy, heterocyclyl, heterocyclylalkyl, heterocycloxy, heterocyclylalkoxy or selected carboxylic acid groups and their derivatives such as esters and amides, alkylsulfonyl, alkylsulfonylamino, alkylsulfonylamino, each which can be optionally substituted； m, n and o independently represents integers from 0 to 5； Y represents a bond, or O, S (O) ₚ or NR⁴ wherein R⁴ represents H, linear or branched C₁₋₆ alkyl, C₁₋₆ cycloalkyl,a. Arilo, heatcycleolo, heatcyclelquilo, cycloalquilo and P represent integers from 0 to 2； W represents c83218c318332626 linear or ramiquilo or c833183626 linear or ramiquilo； V represents or S.Composiciones farmacéuticas que los contienen, y el uso de estos compuestos en medicina. Estos compuestos son adecuados para el tratamiento de enfermedades tales com
