Monica GARCIA-LOPEZ,Carmen ALMANSA-ROSALES,Ana Virginia LLORENTE-FERNANDEZ,Ute CHRISTMANN,Sergio RODRIGUEZ ESCRICH
申请号:
US16301508
公开号:
US20190241544A1
申请日:
2017.05.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to tetrahydropyran and thiopyran derivatives having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.