Synthetic LDL as targeted drug delivery vehicle

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专利权人:

Trudy M. Forte

发明人:

Trudy M. Forte,Mina Nikanjam

申请号：

US12084845

公开号：

US08252338B2

申请日:

2006.11.13

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so as to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of incorporating and targeting therapeutics to cells expressing the LDL receptor for diseases associated with the expression of the LDL receptor such as central nervous system diseases. The invention further provides methods of using such synthetic LDL nanoparticles.

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中国工程科技知识中心

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http://www.ckcest.cn/home/