NG, Lai Guan,EVRARD, Maximilien,KWOK, Immanuel Weng Han
申请号：
SG11202006376W
公开号：
SG11202006376WA
申请日:
2019.01.25
申请国别(地区):
SG
年份:
2020
代理人:
摘要：
Disclosed is a method of characterising and/or separating neutrophils, the method comprises characterising and/or separating the neutrophils into a first population comprising proliferative neutrophils and a second population comprising mature neutrophils, according to the expression of CD101 on the neutrophils. Also disclosed are compositions comprising proliferative neutrophils that are CD10-CD101-, and methods of treatment, diagnostic or prognostic using neutrophils thereof, as well as kits for characterising and/or separating proliferative neutrophils based on the expression of CD101 or CD10. In a preferred embodiment, the population of neutrophils may be characterised as proliferative neutrophils if CD10-CD101-, as immature neutrophils if CD10-CD101+ and as mature neutrophils if CD10+CD101+.
