CARSGEN THERAPEUTICS CO., LTD;SHANGHAI CANCER INSTITUTE
发明人:
Zonghai Li,Zeyan Pan,Zhimin Shi,Bo Song,Peng Wang
申请号：
US15775769
公开号：
US20180327470A1
申请日:
2016.10.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided is a chimeric antigen receptor-modified immune effector cell carrying a procedural death ligand 1 (PD-L1) blocking agent. Also provided is a method for secreting and expressing a PD-L1 blocking agent using the immune effector cell as a carrier to improve the anti-tumour effect of the chimeric antigen receptor-modified immune effector cell.
