ANALOGUES DE L'HORMONE PARATHYROÏDIENNE ET LEURS UTILISATIONS

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专利权人:

THE GENERAL HOSPITAL CORPORATION;CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

GARDELLA, THOMAS, J.,POTTS, JOHN, T.,JUPPNER, HARALD,OKAZAKI, MAKOTO

申请号：

EP11781266

公开号：

EP2569003A4

申请日:

2011.05.12

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Disclosed are two PTH analog ligands, SP-PTH-AAK and Aib-SP-PTH-AAK, that have long-acting activity at the PTH receptor, as demonstrated both in vitro and in vivo. These polypeptides are thus particularly useful in the treatment of diseases, such as hypoparathyroidism, in which long-acting activity is desired. The method of making the analog polypeptides is also disclosed.

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