A microcirculation detection system including a heating device, a photosensitive array and a processing unit is provided. The heating device is used to heat a skin area. The photosensitive array is used to detect outgoing light from the skin area, and output a plurality of brightness variation signals respectively at different time points within a heating period. The processing unit is used to calculate a change of an array energy distribution varied within the heating period according to the plurality of brightness variation signals to accordingly identify a microcirculation state.