Sterilisation of S-nitrosothiols

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专利权人:

Salupont Consulting Ltd

发明人:

Rees, Daryl,Orsi, Antonia

申请号：

AU2016240011

公开号：

AU2016240011A1

申请日:

2016.03.21

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

This invention provides a method of sterilising an S-nitrosothiol, for example S- nitrosoglutathione, without reduction of purity by more than about 5.0% through degradation. The invention allows sterile S-nitrosothiol or a sterile pharmaceutical pre-composition comprising S-nitrosothiol, wherein the S-nitrosothiol is in dry solid form, to be produced. The sterile pharmaceutical pre-composition is mixed with one or more diluents, excipients, carriers, additional active agents, or any combination thereof, for example sterile saline, to prepare a pharmaceutical composition of S-nitrosothiol for use.

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中国工程科技知识中心

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