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ANTICORPS ET MOLECULES APPARENTEES QUI SE LIENT AUX PROTEINES D'ANTIGENE DES CELLULES SOUCHES DE PROSTATE (PROTEINES DE PSCA)
专利权人:
AGENSYS; INC.
发明人:
申请号:
EP05752076.9
公开号:
EP1753871B1
申请日:
2005.05.17
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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