VECTEUR AAV8 AMÉLIORÉ AYANT UNE ACTIVITÉ FONCTIONNELLE AMÉLIORÉE ET PROCÉDÉS D'UTILISATION ASSOCIÉS

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专利权人:

The Children's Hospital of Philadelphia

发明人:

申请号：

EP12746664.7

公开号：

EP2675484B1

申请日:

2012.02.14

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

This application relates to the fields of gene therapy and molecular biology. In accordance with the present invention, an adeno-associated virus (AAV) vector comprising an altered capsid protein is provided. More specifically, this invention provides adeno-associated viral vectors comprising protein capsid variants which accelerate vector breakdown and clearance, thereby reducing undesirable immune responses.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/