PROBLEM TO BE SOLVED: To provide a novel epithelial tight junction formation promoter that is stably available and has an excellent effect, and to provide external preparations, such as pharmaceutical compositions, food and drinks (health-oriented food and drinks are comprised), cosmetic compositions, having epithelial barrier function improving effect containing the same.SOLUTION: The invention provides an epithelial tight junction formation promoter containing as an active ingredient a processed garlic extract containing a sulfur-containing ingredient in high concentration； and pharmaceutical compositions, food and drinks (beauty and health-oriented food and drinks are comprised), and cosmetic compositions containing the same.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】安定供給可能で、効果に優れる新規な上皮タイトジャンクション形成促進剤と、それを配合してなる上皮バリア機能向上効果を有する医薬品組成物、飲食品（健康志向の飲食品を含む）、化粧料組成物等の外用剤を提供する。【解決手段】含硫ニンニク成分を高濃度に含む加工ニンニク抽出物を有効成分とする上皮タイトジャンクション形成促進剤、およびそれを配合した医薬品組成物、飲食品（美容や健康志向の飲食品を含む）、化粧料組成物。【選択図】なし
