MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人:
ANANDAN, Sampath-Kumar,GREENMAN, Kevin,KAMAL, Zeeshan,SINGH, Vijay P.
申请号:
SG11202000239X
公开号:
SG11202000239XA
申请日:
2018.07.12
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: (I) (II) or a pharmaceutically acceptable salt thereof.