VECT-HORUS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
发明人:
MICHEL KHRESTCHATISKY,MARION DAVID,YVES MOLINO,PATRICK VLIEGHE
申请号:
FR0857159
公开号:
FR2937322B1
申请日:
2008.10.22
申请国别(地区):
FR
年份:
2013
代理人:
摘要:
The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).