Fiorella Petronzelli;Rita De Santis;Paolo Maria Comoglio;Carla Boccaccio
发明人:
Carla Boccaccio,Paolo Maria Comoglio,Fiorella Petronzelli,Rita De Santis
申请号:
US13423830
公开号:
US20120237524A1
申请日:
2012.03.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Met inhibitor and/or nucleotide sequence encoding a Met inhibitor for use in the treatment of patients suffering from a cancer for reducing and/or abrogating patients' resistance to radiotherapy, wherein the Met inhibitor is selected among: i) an anti-Met monoclonal antibody, ii) a genetically engineered antibody containing the complementarity determining regions (CDRs) of the anti-Met monoclonal antibody, and iii) a fragment of (i) or (ii) containing the complementarity determining regions (CDRs) of the anti-Met monoclonal antibody, or combinations thereof.