This invention relates to compositions for combating ectoparasites and endoparasites in animals, comprising at least one 1-arylpyrazole, at least one macrocyclic lactone, at least one insect growth regulator, and at least one anthelmintic compound in combination with a pharmaceutically acceptable carrier. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.本發明係關於防治動物之體外寄生蟲及體內寄生蟲之組合物，其包含至少一種1-芳基吡唑、至少一種大環內酯、至少一種昆蟲生長調節劑、及至少一種驅蟲化合物與醫藥上可接受之載劑組合。本發明亦提供用於根除、控制、及預防動物之寄生蟲感染及侵擾之改良方法，其包含向有需要之動物投與本發明組合物。
