This invention concerns in general treatment of diseases and pathological conditions with anti-VEGF antibodies. More specifically, the invention concerns the treatment of human patients susceptible to or diagnosed with cancer using an anti-VEGF antibody, in combination with one or more additional anti-tumor therapeutic agents in previously treated metastatic breast cancer.本發明概言之係關於使用抗-VEGF抗體來治療疾病及病理學病狀。更具體而言,本發明係關於使用抗-VEGF抗體與一或多種額外抗腫瘤治療劑之組合用於治療先前曾治療過轉移性乳癌的易罹患或經診斷已罹患癌症之人類患者。