The present invention relates to compound characterized by a general formula 1,wherein- R1 is a aryl or a heteroaryl, and- R2 and R3- independently of each other are hydrogen or a C1-C5 alkyl, or- together are a C3 or C4 alkyl forming a 5- or 6 membered ring,for use in a method for preventing or treating of heart failure, hypertension or cardiac hypertrophy.
