PURPOSE: A cosmetic composition containing dihydromyricetin or derivative of thereof is provided to promote collagen generation of damaged skin tissue. CONSTITUTION: A cosmetic composition for skin regeneration contains dihydromyricetin of chemical formula 1 and its derivative. The dihydromyricetin or its derivative is isolated from Xanthoceras sorbifolia, Catha edulis, Gattung Rhododendron, Ampelopsis brevipedunculala, Ampelopsis meliaefolia, Cercidiphyllum japonicum or Ampelopsis grossendentata. The composition is used the form of solution, suspension, emulsion, paste, gel, cream, lotion, powder soap, surfactant-containing cleansing, foundation, or spray.본 발명은 디하이드로미리세틴(Dihydromyricetin) 또는 이의 유도체를 포함하는 피부재생용 화장료 조성물에 관한 것으로, 뛰어난 보습 효과 및 손상된 피부 조직의 콜라겐 생성을 촉진함으로써 탁월한 피부재생 효과 및 피부 탄력성 개선 효과를 갖는다.