Donald Pivonka;Anna-Karin Tidén;Anders Bögevig;Yvonne Lo-Alfredsson
发明人:
Anders Bögevig,Yvonne Lo-Alfredsson,Donald Pivonka,Anna-Karin Tidén
申请号：
US12938490
公开号：
US08859568B2
申请日:
2010.11.03
申请国别(地区):
US
年份:
2014
代理人:
摘要：
There are disclosed novel compounds of formula (I)wherein R1, R12, L, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof； together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders, cardiovascular disorders and respiratory disorders.
