Graciela de los Ángeles Aguilera Suárez,Carmen Miguel Gómez Sánchez,Martha Rosaura Juárez Lora
申请号：
US15319287
公开号：
US09895362B2
申请日:
2014.06.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The combination of gabapentin with lysine clonixinate (CLG) makes it possible to relieve neuropathic pain caused both by diabetic neuropathy and by an injury to the nerve. The CLG combination produces a synergy in the antiallodynic effect, when the allodynia has been generated by direct mechanical damage to nervous tissue or when it has been produced as a result of a diabetic pathology. The therapeutic effect of the CLG combination is 3 to 11 times greater than the effect of each of the drugs separately.The CLG combination is safe, because it shows no adverse effects on motor activity or alterations in neurological parameters nor damage to the liver or kidney.
