ERNING XIA,SRINI VENKATESH,SUSAN E. BURKE,VICKI L. BARNIAK
申请号：
BRPI0821937
公开号：
BRPI0821937B1
申请日:
2008.10.10
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
Ophthalmic compositions that comprise 0.1 ppm to 10 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof； 0.005 wt.% to 0.15 wt.% of hyaluronic acid； and 0.01 wt.% to 1.0 wt.% of an amphoteric surfactant of general formula I wherein R 1 is R or -(CH 2 ) n -NHC(O)R, wherein R is a C 8 -C 16 alkyl optionally substituted with hydroxyl and n is 2, 3 or 4； R 2 and R 3 are each independently selected from methyl, ethyl, propyl or iso-propyl； and R 4 is a C 2 -C 8 alkylene optionally substituted with hydroxyl. The invention is also direct to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.
