Hsing-Wen Sung,Mei-Chin Chen,Po-Wei Lee,Hosheng Tu
申请号：
US12381684
公开号：
US08137697B1
申请日:
2009.03.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention discloses the biodegradable nanoparticle for use in nanoparticle projectile bombardment as a carrier for administering nucleic acid, DNA, RNA or siRNAs transdermally to an animal subject. The nanoparticles are composed of positively charged chitosan substrate and the nucleic acid encapsulated within the nanoparticles or electrostatically loaded on the exterior surface of the nanoparticles.
