Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd.
发明人:
申请号:
EP18793712.3
公开号:
EP3684794A1
申请日:
2018.09.17
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention provides prodrugs of somatostatin peptide and peptide analogs that are tissue permeable and oral bioavailable and enable activity of the somatostatin analog at the circulation or target tissue after cleavage of charge-masking lipophilic moieties. Pharmaceutical compositions comprising these prodrugs and their use in therapy and diagnosis are also provided.