Systems and methods for fixation of fractures of a long bone Systems and methods for fixation of fracture of a long bone comprising of at least one intramedullary nail having one or more holes and at least one external plate placed along the external body of one or both of the ends of a long bone, wherein one or more of a plate is fixed to the external body of the long bone by inserting one or more of a fastening device through one or more of holes in the one or more of plates, and wherein one or more of the said fastening devices enter or penetrate the intramedullary nails through the one or more of holes in the intramedullary nails. The system may be used for fixation of the cancellous bone or the cortical bone.